eBook

79: Some Thyrotropic Agents (IARC Monographs on the Evaluation of the Carcinogenic Risks to Humans)

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79: Some Thyrotropic Agents (IARC Monographs on the Evaluation of the Carcinogenic Risks to Humans)
Author: -
eBook Title: 79: Some Thyrotropic Agents (IARC Monographs on the Evaluation of the Carcinogenic Risks to Humans)
Category: Other
Rating: 5.0
Votes: 413
Formats: PDF, FB2, EPUB, DJVU
ISBN: 9283212797
ISBN13: 978-9283212799
Publisher: World Health Organization; 1 edition (November 1, 2001)
Language: English
Subcategory: Medicine & Health Sciences
This volume evaluates carcinogenicity to humans of 19 chemicals that are carcinogenic to the thyroid follicular-cell epithelium in rodents. These included some so-called “anti-thyroid” drugs (methimazole, methylthiouracil, propylthiou-racil and thiouracil); some sedatives (doxylamine succinate and phenobarbital); and some other drugs including the systemic antifungal antibiotic griseofulvin, the diuretic spironolactone, and the antibacterial sulfa drugs sulfamethazine and sulfamethoxazole. Other chemicals are or have been used in agriculture as pesticides (amitrole, chlordane/heptachlor, hexachlo-robenzene and toxaphene), in foods and cosmetics (kojic acid), in hair dyes (2 4-diaminoanisole) or as industrial chemicals (N N'-diethylthiourea, ethylenethiourea and thiourea).

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